Something went badly wrong and the error is still being propagated in medical schools today. Last year I met a medical student who was taught that Dr Ancel Keys paper was actually correct – in spite of decades of research contradicting Ancel’s erroneous hypothesis. This error has built a $30,000,000,000 drugs empire so it must be a ‘commercially truth’ built upon a ‘scientific error’. So we have to take the drug because it makes commercial sense to do so, even though the risks outstrip any minor benefit claims you can massage out of the inconclusive meta-analysis of combined trial data.