Link

Some quotes from Prof. Nyström translated into English from Dr. Eenfeldt:

Butter, olive oil, heavy cream, and bacon are not harmful foods. Quite the opposite. Fat is the best thing for those who want to lose weight. And there are no connections between a high fat intake and cardiovascular disease.

On Monday, SBU, the Swedish Council on Health Technology Assessment, dropped a bombshell. After a two-year long inquiry, reviewing 16,000 studies, the report “Dietary Treatment for Obesity” upends the conventional dietary guidelines for obese or diabetic people.

For a long time, the health care system has given the public advice to avoid fat, saturated fat in particular, and calories. A low-carb diet (LCHF – Low Carb High Fat, is actually a Swedish “invention”) has been dismissed as harmful, a humbug and as being a fad diet lacking any scientific basis.

Instead, the health care system has urged diabetics to eat a lot of fruit (=sugar) and low-fat products with considerable amounts of sugar or artificial sweeteners, the latter a dangerous trigger for the sugar-addicted person.

This report turns the current concepts upside down and advocates a low-carbohydrate, high-fat diet, as the most effective weapon against obesity.

The expert committee consisted of ten physicians, and several of them were skeptics to low-carbohydrate diets at the beginning of the investigation.

Sweden Becomes First Western Nation to Reject Low-fat Diet Dogma in Favor of Low-carb High-fat Nutrition

Link

Congratulation to Rothman, Schekman and Südhof for their Nobel Prize recognising an amazing set of discoveries about machinery regulating vesicle traffic.

What is now remarkable about the mechanism is the role of Cholesterol in facilitating the wrapping and release machinery. In 2008 Xia et al. established that it only took a 10% fall in membrane cholesterol to bring the whole process of vesicle release to a stop. (doi: 10.1210/en.2008-0161)

Cholesterol was so ubiquitous, and very erroneously thought to be a causative agent in disease, its vital roles in vesicle formation and release were overlooked. Now that the vesicles are a hot topic I hope to see cholesterol recognised for its role in all this vesicle traffic.

Wainwright G, Mascitelli L, Goldstein MR. Cholesterol lowering therapies and membrane cholesterol. Stable plaque at the expense of unstable membranes? Arch Med Sci. 2009;5:289–95.

Nobel Prizes, Vesicle Traffic and Cholesterol

Link

From Dr Stephanie Seneff’s Blog Pages

Cholesterol Sulphate

The skin produces cholesterol sulfate in large quantities when it is exposed to sunlight. Our theory suggests that the skin actually synthesizes sulfate from sulfide, capturing energy from sunlight in the form of the sulfate molecule, thus acting as a solar-powered battery. The sulfate is then shipped to all the cells of the body, carried on the back of the cholesterol molecule.

Evidence of the benefits of sun exposure to the heart is compelling, as evidenced by a study conducted to investigate the relationship between geography and cardiovascular disease (Grimes et al., 1996). Through population statistics, the study showed a consistent and striking inverse linear relationship between cardiovascular deaths and estimated sunlight exposure, taking into account percentage of sunny days as well as latitude and altitude effects. For instance, the cardiovascular-related death rate for men between the ages of 55 and 64 was 761 in Belfast, Ireland but only 175 in Toulouse, France.

Cholesterol sulfate is very versatile. It is water soluble so it can travel freely in the blood stream, and it enters cell membranes ten times as readily as cholesterol, so it can easily resupply cholesterol to cells. The skeletal and heart muscle cells make good use of the sulfate as well, converting it back to sulfide, and synthesizing ATP in the process, thus recovering the energy from sunlight. This decreases the burden on the mitochondria to produce energy. The oxygen released from the sulfate molecule is a safe source of oxygen for the citric oxide cycle in the mitochondria.

So, in my view, the best way to avoid heart disease is to assure an abundance of an alternative supply of cholesterol sulfate. First of all, this means eating foods that are rich in both cholesterol and sulfur. Eggs are an optimal food, as they are well supplied with both of these nutrients. But secondly, this means making sure you get plenty of sun exposure to the skin. This idea flies in the face of the advice from medical experts in the United States to avoid the sun for fear of skin cancer. I believe that the excessive use of sunscreen has contributed significantly, along with excess fructose consumption, to the current epidemic in heart disease. And the natural tan that develops upon sun exposure offers far better protection from skin cancer than the chemicals in sunscreens.

Cholesterol Sulphate and Heart Disease

Sugar Damage and Dementia

A normal brain requires reliable supplies of fatty nutrients supplied by the liver as LDL. LDLs are fatty packets of nutrients travelling in the blood to feed the brain and other organs.  LDL receptors on the organs recognise the LDL packets and absorb them. The ‘empty packets’ (HDL), carrying waste for recycling, return to the liver via the blood stream.
image

Over time sugars damage the LDL labels, and thus stop the nutrients from being recognised by the brain’s LDL receptors. Consequently LDL stays in the blood and less HDL packets are produced.  This raised LDL. and lower HDL. is associated with poor health. The cause is sugar-damage. image

Sugar damage causes the brain to be starved of vital fat and cholesterol.

Treatments which lower ‘LDL cholesterol’ do not help. They further deprive the brain of LDL, The brain and other organs become starved of fatty nutrients. Meanwhile, any excess dietary sugars (fructose & glucose) become the cause many ‘diabetes associated’ illnesses.

Fructose, which is increasingly being added to food products, is the new problem sugar. It is more reactive and 10 times more damaging than glucose.

The vital fatty nutrients in LDL are falsely called ‘Bad Cholesterol’.

Raised blood lipids (LDL) are a symptom, and again the cause is sugar-damage.

Is it any wonder that years of the dogmatic policy of ‘Cholesterol Reduction’ have failed to deliver health benefits, and is fraught with problems such as muscle wastage, diabetes and dementia?

The above is a very simplified overview of our paper. If you click on this link you can read our full paper, as published in the Archives of Medical Science.

Click here for our Dementia Paper

(These are ‘free access’ publications)

Video

isomorphismes:

John Bonner’s slime mould movies (por princetonuniversity)

  • some slimes altruistically sacrifice themselves,
  • the individuals communicate based on micro rules to make a macro (emergent) decision “together”, yet without a central planning slime
  • the slimes move around (like animals), yet also form a “stem” and grow upwards (like plants), yet also shoot spores out of the top (like fungi).

Quantum entangled scentience. All life is one with all matter. Just a thought!

Image

bpod-mrc:

22 May 2013

Keeping in Shape

Stretch your skin and it springs back to shape – a property also possessed by the lining of your throat, inner ear, blood vessels and many other body parts. This springy tension is due to each surface cell having a tiny belt, formed by the proteins myosin and actin, wrapped around it, rather like an elastic band. Scientists have discovered that these belts are interlinked so that their stretching and squeezing actions spread like waves through the millions of cells, controlling the shape and movement of the surface (epithelial) tissue. Pictured (bottom) is a normal arrangement of surface cells of a rat’s intestine, with actin stained red and cell boundaries green. When myosin is chemically deactivated, the protein belts stop working, causing the cells to drift apart (top).

Written by Mick Warwicker

The Vital Role of Cholesterol in Our Bodies

We make a few grams of cholesterol in our bodies everyday. Not because it’s dangerous but because it’s vital. Cholesterol reduction is driven by orthodoxy, dogma and money. A few researchers have tried to blow the whistle on this madness but being scientific and truthful is not enough.

Key Fact 1:  In the cell there needs to be one molecule of cholesterol for every 4 molecules of lipid.  A small reduction will prevent cells taking in and releasing vital nutrients and messages. (reference 1)

Key Fact 2: Reducing the cholesterol in the cell wall makes them leaky, saggy and weak. (reference 2)

Every year Cholesterol Reduction is worth tens of billions of dollars to the food and drugs industries and it can kill. I ask is it worth it?

Reference Links

(reference 1)

Xia F, Xie L, Mihic A, et al. Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells. Endocrinology 2008; 149: 5136-45.

(reference 2)

T.H. Haines ‘Do Sterols reduce leaks in Bilipid layers?’ Progress in Lipid Research 40 (2001) 299–324

Our research review Cholesterol Lowering Therapy  is available free in the Archives of Medical Science on this link

Acknowledgements

Dr Luca Mascitelli

Dr Duane Graveline

and members of ‘The International Network of Cholesterol Skeptics’