Tag Archives: fat

The Cholesterol Story – An Essay

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The final edition of Dark Side of Statins by Dr Duane Gravelin MD explains why the drug has been such a huge disappointment and damaging mistake to a large proportion of patients. In it he included my essay “The Wonder of Cholesterol” which is a simplified explanation of why cholesterol is vital to our wellbeing and any attempt to lower it was always doomed to cause ill health. A key point in all this was the failure to recognise that the real cause of lipid dysfunction was sugar-damage (glycosylation) to the lipid receptors in all the organs of the body. We now have huge numbers of patients who are using carbohydrate restriction to reverse age-related diseases like mature-onset diabetes (T2D). Data being recorded by their Health Carers shows that the lipid profile (LDL/HDL) improves as the sugar-damage, as measured by HbA1c, is lowered.

Fats, Sugar, Salt & Cholesterol -the video interview!

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The interest in this video has been amazing and thank you to all who have watched it all. You don’t have to  because those with less time here are the “bite-sized” topic-based links below.

Interview

Video Index – Click on the topics to jump in:-

International Presentation Link

Useful References (linked)

  1. Ravnskov U, McCully KS Ann Clin Lab Sci. 2009 Winter;39(1):3-16.Review and Hypothesis: Vulnerable plaque formation from obstruction of Vasa vasorum by homocysteinylated and oxidized lipoprotein aggregates complexed with microbial remnants and LDL autoantibodies.
  2. Wainwright G, Mascitelli L, Goldstein M. Archives of Medical Science. 2009;5(3):289-295. Review paper Cholesterol-lowering therapy and cell membranes. Stable plaque at the expense of unstable membranes?.
  3. Seneff S, Wainwright G, Mascitelli L. Review paper Is the metabolic syndrome caused by a high fructose, and relatively low fat, low cholesterol diet?. Archives of Medical Science. 2011;7(1):8-20. doi:10.5114/aoms.2011.20598
  4. Seneff S, Wainwright G, Mascitelli L. Review Paper Nutrition and Alzheimer’s disease: The detrimental role of a high carbohydrate diet
    Seneff, Stephanie et al. European Journal of Internal Medicine , Volume 22 , Issue 2 , 134 –

“Low Carb” Lifestyle for a better approach to Weight-Loss & Health.

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It seems obvious now that if your GP tells you that you can no longer process the sugars in your blood (diagnosing pre-diabetes) you can fix it by eating less sugar generating foods (Carbs).

So why isn’t everyone getting slimmer and healthier.

The dietary advice we get from many agencies is still contradictory and wrong. We’re told to eat less fat, salt and sugar and then told to eat starchy (sugar generating foods) and vegetable oils – All bad advice for humans

Clearly this ain’t working but something better is now starting to happen.

A small but growing number of people have decided that if they can’t handle Carbohydrates (Diabetes) they should limit them to less than they burn in a day. That way they will bring blood sugar down towards normal and stop storing the excess sugar in their expanding waistlines. They are becoming slimmer and healthier.

Seven years ago after publishing a research review I decided to get myself checked. A Diabetic Clinician told me that I needed insulin and was was on a one-way journey of decline. They said all I could hope was to slow it down. With my research knowledge I declined the advice on offer and requested a further review in 3 months time.  Eating lots of Carbs was now going to be harmful! I lowered my carbohydrate intake to 100g per day (a modest but easy target). , I knew I could burn all that carbohydrate in a day,  At the review my astonished Clinician said I was on well on my way toward good control without medical intervention. At that clinician failed to investigate what I had done!

Two years later  I softened my stance and accepted Metformin thinking it was OK and would  help me control my blood sugars. I settled into a stable period of good sugar control, improved waist line and my weight.

Two years ago, I was inspired by a gadget which I could wear that recorded my sugar level all day and graphed it on my laptop. This allowed me to find out more about how my lifestyle was affecting my sugar. Diet, Activity and stress all play their part. But in 2017 I was told I was no longer diabetic.

2017 May Review copy (2017_05_12 09_45_27 UTC)

In remission as a prediabetic I stopped needing Metformin, but I was too late stopping. My dentist noticed a problem on my tongue and after further investigation suggested I should get checked out for a vitamin B12 deficiency. A cascade of problems was now in play.

I am now well and moving back to diabetes remission with full health thanks to an amazing and timely intervention by the Yorkshire Heart Centre, They too accepted my reasons for not taking statins (a separate blog) and I am now only taking a cardio-aspirin once a day, walking up to 14 miles a day in the dales and feeling really good

I have to say that the dietary advice is at best patchy but the Low Carb Lifestyle is now acknowledged and aapproved by the NHS (UK) for reversing mature-onset diabetes. In fact a lot of troubles that are thought of as “Old Age” are improved by Low Carb Lifestyle, Mindfulness and Exercise.

Cell Walls – Essential Role of Fats & Cholesterol

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The outer and inner membranes protect and define the cells in the tissues of our bodies. They give them shape and strength. These membranes organise, support and protect the proteins (enzymes) that give function and purpose to the tissues and organs of our bodies.

Cell Membranes are made of fat (lipids) and cholesterol. To work and protect the cell there has to be at least 1 cholesterol molecule for every 4 fat molecules.  Less cholesterol causes the membrane to become weak and leaky.
The maintenance of organs and tissues relies on a regular supply of fats and fat soluble nutrients. This supply comes from the large LDL lipid droplets which are recognised and absorbed by the LDL receptors on the cells. The recycling waste involves the return of smaller HDL  lipid droplets to the liver via the blood stream.

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As we age ours cells LDL receptors can become damaged by sugar leading to poor maintenance of the membranes.  The cell has a shortage of lipids (fats) and cholesterol. Cell walls  becomes leaky and prone to fail. LDL lipids are left unused in the blood stream. HDL lipids are not being returned.

As we age what we we required is a reduction in damage caused by excess blood sugars (glucose and fructose) together with an adequate supply of fats and cholesterol.  

This is the basis of the success of the Low-Carbohydrate High-Fat diets in addressing the modern dietary health issues.

Published research on cell membranes and lipids is at complete odds with modern medical practices and much dietary guidance.  Statins and low fat diets are misguided attempts to prevent fatty nutrients from entering the blood stream by blocking the production of mevalonate.  Mevalonate is used to make steroids hormones, cholesterol, signalling molecules, dolichols and co-enzyme Q10 etc – a whole series of vital health promoting substances.

The Statin-Damage Triad is a modern health crisis progressively brought on by a combination of 3 lifestyle factors: Excess Blood Sugar, Low Dietary Fat intake and statin medications.

Links:  The supporting references to published research are contained in my conference paper  ‘The High-Cholesterol Paradox’ which was especially requested to make facts and history widely accessible.

Link

The inability of current recommendations to control the epidemic of diabetes, the specific failure of the prevailing low-fat diets to improve obesity, cardiovascular risk or general health and the persistent reports of some serious side effects of commonly prescribed diabetic medications, in combination with the continued success of low-carbohydrate diets in the treatment of diabetes and metabolic syndrome without significant side effects, point to the need for a reappraisal of dietary guidelines.

•They present major evidence for low-carbohydrate diets as first approach for diabetes.
•Such diets reliably reduce high blood glucose, the most salient feature of diabetes.

•Benefits do not require weight loss although nothing is better for weight reduction.

•Carbohydrate-restricted diets reduce or eliminate medication.

•There are no side effects comparable to those seen in intensive treatment with drugs.
Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman
EC, Accurso A, Frasetto L, McFarlane S, Nielsen JV, Krarup T, Gower BA, Saslow L, Roth KS, Vernon MC, Volek JS, Wilshire GB, Dahlqvist A, Sundberg R, Childers A, Morrison K, Manninen AH, Dashti H, Wood RJ, Wortman J, Worm N, Dietary Carbohydrate restriction as the first approach in diabetes
management. Critical review and evidence base, Nutrition  (2014), doi: 10.1016/j.nut.2014.06.011.

You can’t get funding very easily for lifestyle trials because there is no profit to be made. Or is there? Medical Insurance and NHS costs would be reduced dramatically – so there is a cost reduction motive for funding!

Dietary Carbohydrate restriction as the first approach in diabetes management

The ‘High Cholesterol’ Paradox

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For some people, being told they have ‘high cholesterol’ suggests a decline, for others it is a sign of healthy longevity. What is really going on?

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The real story is the way in which high dietary levels of refined sugars such as Fructose can adversely modify our lipid-protein-labels and break the fatty nutrition cycle supplying all our organs.

Normally high lipid levels with good ratios of LDL (larger nutrient packages) and HDL (returning ’empty’ packages for recycling) are seen in people with healthy long life prospects. 

When the LDL package address (protein marker) is sugar-damaged (glycated) LDL backs up in the blood and less HDL is recycled. The blood lipids are up but the organs can’t use it. e.g The brain is starved of vital fat-soluble nutrients. Taking medication to block cholesterol production will lower blood lipids BUT…. the brain, muscles etc. are  still starved of vital fat-soluble nutrition and the outcome worsens.

The HbA1c test for sugar-damage in the blood protein hemoglobin looks likely to be a great indicator for sugar damage in general so..

‘High Cholesterol’ with good HbA1c levels is a healthy sign.

‘High Cholesterol’ with poor HbA1c levels is a very unhealthy sign.

THE REAL STORY IS SUGAR-DAMAGE

Link

The diet was hatched in Poland some 40 years ago by Dr. Jan Kwasniewski, who started developing it while working as a dietician for a military sanitarium in Ciechocinek, Poland. There he observed that many of his patients were sick, “not because of any pathogenic factors … but the result of one underlying cause – bad nutrition,” according to his English language “Optimal Nutrition” book. After experimenting on his family and himself, Kwasniewski concluded that the ideal nutritional combo came from eating three grams of fat for every one gram of protein and half a gram of carbohydrates.

Petro Dobromylskyj

Praise the Lard – indeed!