A Fructose Damage Blood Test?

HbA1c sugar damaged blood protein – are we measuring the
most important thing.?

Whilst I have no doubt that measuring this is a great way to
detect potential sugar damage, it may only be the tip of the iceberg.

Fructose damage should be measured. Fructose has been
increasing in our foods since the now discredited ‘low-fat high-sugar’ food
fads hit the markets almost 40 years ago.

On a ‘High-Fat Low-Car’ regime I have found that keeping below
70mmol/mol (6%) has prevented all obvious diabetes symptoms from developing.

Avoiding refined Fructose products may be most important
because Fructose is 7x more reactive and damaging towards the bodies protein
mechanisms and enzymes.  The benefits of
avoiding high-fructose foods (HFCS on labels) may be many times greater than
simply managing glucose for modern type 2 diabetics if over the last 40 years HFCS
fructose additives are 7x more dangerous than glucose when it come to sugar damage!

We urgently need
to routinely test for Fructose damage in a blood test!

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Autoimmunity and T2D

My anecdotal experience and studies have shown me thIs:-

Glycoproteins are important on cell surfaces (extracellular matrix) they are anchored by dolichols and form an important part of the communication between tissue and immune system, with recognisable sequences of sugars deliberately assembled for the matrix. This is structural sugars in the body assembled by enzymes in the normal cellular machinery.

Glycation damaged proteins (AGE). These are exposed proteins who randomly become attached to a mono-sugar (usually glucose but recently increasingly fructose) attaching to lysine by the maillard reaction).

In cooking at oven temps this is a desirable and flavoursome reaction at some speed.

In diabetics this is a very slow (decades at body temp) degradation of lipid receptor mechanisms, elastins and collagens.

Auto-immunes and T2D

The body has a clean-up immune response to random AGE mono-sugar attack, which is overwhelmed as we age and develop T2D (over decades). The suagr damage effect is present in many tissues showing a strong immune response (arthritis, eczema) which often respond well to carbohydrate restriction and increased dietary use of ‘essential fatty acids’.

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The inability of current recommendations to control the epidemic of diabetes, the specific failure of the prevailing low-fat diets to improve obesity, cardiovascular risk or general health and the persistent reports of some serious side effects of commonly prescribed diabetic medications, in combination with the continued success of low-carbohydrate diets in the treatment of diabetes and metabolic syndrome without significant side effects, point to the need for a reappraisal of dietary guidelines.

•They present major evidence for low-carbohydrate diets as first approach for diabetes.
Such diets reliably reduce high blood glucose, the most salient feature of diabetes.

Benefits do not require weight loss although nothing is better for weight reduction.

Carbohydrate-restricted diets reduce or eliminate medication.

There are no side effects comparable to those seen in intensive treatment with drugs.
Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman
EC, Accurso A, Frasetto L, McFarlane S, Nielsen JV, Krarup T, Gower BA, Saslow L, Roth KS, Vernon MC, Volek JS, Wilshire GB, Dahlqvist A, Sundberg R, Childers A, Morrison K, Manninen AH, Dashti H, Wood RJ, Wortman J, Worm N, Dietary Carbohydrate restriction as the first approach in diabetes
management. Critical review and evidence base, Nutrition  (2014), doi: 10.1016/j.nut.2014.06.011.

You can’t get funding very easily for lifestyle trials because there is no profit to be made. Or is there? Medical Insurance and NHS costs would be reduced dramatically – so there is a cost reduction motive for funding!

Dietary Carbohydrate restriction as the first approach in diabetes management

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A note to Dr Briffa from a T2 diabetic

I had my 6 monthly diabetes check-up last Wednesday. The diabetes consultant was really happy with all of my figures on cholesterol, triglycerides, blood pressure, weight (I’ve lost another 4 kg since February without really trying), kidney and liver function are excellent – in fact he was really impressed and asked me what I was doing to get these improvements.

Simple, I said, I’ve stopped eating wheat in all its forms and grains in general, I avoid rice and all potato products. I eat animal fat and the only oil that I use is extra virgin olive oil. Breakfast is typically a one-egg omelette and with a small amount of bacon, smoked salmon or Parma ham. I have spinach or other leafy greens and tomatoes. Lunch is often not taken as I do not feel hungry until 6.00 pm when I have my evening meal. Another small portion of meat and plenty of veggies. The only fruit that I have are a few blueberries, wild strawberries (when they are available) and raspberries – and I mean a few.

I sleep better than ever, don’t feel tired and have lost weight. I really ought to exercise though, that is the only flaw in my regime.

“No, you MUST eat some carbohydrates” he said.

“I do, I told you, I eat plenty of vegetables.” I said.

“No, no, starchy carbohydrates, you NEED them”

“Why do I NEED them?”

“For energy, your body needs carbohydrates for energy” came his concerned reply.

“How do you think that I’ve managed to survive since you last saw me then? And, you told me how pleased you were with all of my readings – doesn’t that suggest that I’m doing fine without refined, starchy carbohydrates?”

He had no reply other than to repeat to me that I MUST eat carbohydrates for energy.

I urged him to read Primal Body, Primal Mind by Nora T Gedgaudas and made him write it down. I could see that he wasn’t convinced. So, I told him that the bullshit that he’d been taught by the food industry-research funded nonsense that the Government taught him is causing all of the major health problems that he has to deal with every day.

I also said that I throw a fat-fuelled log onto the fire in the morning rather than the carbohydrate kindling throughout the day to keep me provided with energy and avoid the feeling of hunger. Again, nothing seemed to penetrate that simple head of his; it was full of the guff that he’d been taught not to question.

Diabetic transforms his health with a low-carb diet, BUT his doctor urges him to eat more carbs