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AGEs (Advanced Glycaemic End-products)

The other cause of sugar damage is the uncontrolled (non-enzymic) attachment of excess sugar molecules (e.g. fructose and glucose) to proteins (such as collagen, elastin and receptors) around the body.  Over time this gives rise to sugar-damaged proteins known as appropriately as Advanced Glycaemic End-products (AGEs). These AGEs cause, joints, arteries, heart, lungs and skin etc. to lose their elasticity.

The transport of the fat soluble nutrients (including vitamins A, D & E )  to all the organs of the body rely upon Lipids (fatty droplets) produced by the liver and circulating in the blood in the blood.   A simplified version of this mechanism has the liver sending large particles (LDL) to deliver the nutrients and the tissues returning smaller particles (HDL) for recycling.  The particles have apolipoproteins (APO) as labels  the to identify their destination and purpose. Matching receptors are deployed on tissues to latch onto the lipids droplets they require.   When the labels and receptors are damaged by attached sugars, the tissues cannot get the fats they require and the fats are scavenged by visceral fat cells in the abdomen.  This causes a cascade leading to a variety of AGE related diseases as we age.

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Oxidative Stress

One way is the damage caused by reactive oxygen species (ROS) that are produced by the burning of blood sugar (Glucose) and oxygen in our cells to  produce energy. The free radicals produced by this can cause oxidation damage to surrounding tissues (oxidative stress). The body uses a variety of anti-oxidants (e.g. cholesterol & CoQ10) to control or limit such damage but these can be overwhelmed.  The rate of damage may exceed the rate of repair with excessive use of energy from sugar.

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Sugar Damage

A spectrum of diseases, in modern civilisation, are caused by sugar damage. Such diseases include Diabetes, Heart Diseases, Alzheimer’s and a variety of conditions such as hardening of arteries, raised blood pressure, abdominal obesity and ageing skin. 

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lizwainwright:

‘Don’t be disgusting! You’ve no right to talk about my Mother like that. She was right about you, she always said you didn’t know how to behave, and that you dressed like a tart. Look at you now, tarted up in that yellow dress like, like it was a day out in Blackpool not the day of my Father’s funeral!’

 ‘I put this on because your Dad said he liked it, it was like a bit of sunshine, he said.’

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lizwainwright:

The Girl who wasn’t Good Enough is the first of The Lynda Collins Trilogy.

Liz is currently writing books 2 and 3. The original Book 3 was the first of the books to be written and it was suggested that readers would want to know where Lynda Collins’ background. The writing of books 1 & 2 will cause a major revision of book 3. Liz is very enthusiastic about the whole project. Reactions to book 1 have exceeded expectations.

Liz’s Radio Drama & Stage Plays are also available in paperback.

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lizwainwright:

The Girl who wasn’t Good Enough is the first of The Lynda Collins Trilogy.

Liz is currently writing books 2 and 3. The original Book 3 was the first of the books to be written and it was suggested that readers would want to know where Lynda Collins’ background. The writing of books 1 & 2 will cause a major revision of book 3. Liz is very enthusiastic about the whole project. Reactions to book 1 have exceeded expectations.

Liz’s Radio Drama & Stage Plays are also available in paperback.

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The perfect storm for an obesity epidemic – Eat fat producing carbohydrates and pump our foods full of fructose and glucose. Fructose is 10 times more damaging than glucose. What do you put into ‘low fat’ foods to make them palatable – Fructose? Obesity and a range mature-onset medical-conditions accelerated after this combination of circumstances in the late 1970s. Eat sugar-generating foods and stop eating fats – and watch you belly expand!!!