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Some quotes from Prof. Nyström translated into English from Dr. Eenfeldt:

Butter, olive oil, heavy cream, and bacon are not harmful foods. Quite the opposite. Fat is the best thing for those who want to lose weight. And there are no connections between a high fat intake and cardiovascular disease.

On Monday, SBU, the Swedish Council on Health Technology Assessment, dropped a bombshell. After a two-year long inquiry, reviewing 16,000 studies, the report “Dietary Treatment for Obesity” upends the conventional dietary guidelines for obese or diabetic people.

For a long time, the health care system has given the public advice to avoid fat, saturated fat in particular, and calories. A low-carb diet (LCHF – Low Carb High Fat, is actually a Swedish “invention”) has been dismissed as harmful, a humbug and as being a fad diet lacking any scientific basis.

Instead, the health care system has urged diabetics to eat a lot of fruit (=sugar) and low-fat products with considerable amounts of sugar or artificial sweeteners, the latter a dangerous trigger for the sugar-addicted person.

This report turns the current concepts upside down and advocates a low-carbohydrate, high-fat diet, as the most effective weapon against obesity.

The expert committee consisted of ten physicians, and several of them were skeptics to low-carbohydrate diets at the beginning of the investigation.

Sweden Becomes First Western Nation to Reject Low-fat Diet Dogma in Favor of Low-carb High-fat Nutrition

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Congratulation to Rothman, Schekman and Südhof for their Nobel Prize recognising an amazing set of discoveries about machinery regulating vesicle traffic.

What is now remarkable about the mechanism is the role of Cholesterol in facilitating the wrapping and release machinery. In 2008 Xia et al. established that it only took a 10% fall in membrane cholesterol to bring the whole process of vesicle release to a stop. (doi: 10.1210/en.2008-0161)

Cholesterol was so ubiquitous, and very erroneously thought to be a causative agent in disease, its vital roles in vesicle formation and release were overlooked. Now that the vesicles are a hot topic I hope to see cholesterol recognised for its role in all this vesicle traffic.

Wainwright G, Mascitelli L, Goldstein MR. Cholesterol lowering therapies and membrane cholesterol. Stable plaque at the expense of unstable membranes? Arch Med Sci. 2009;5:289–95.

Nobel Prizes, Vesicle Traffic and Cholesterol

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From Dr Stephanie Seneff’s Blog Pages

Cholesterol Sulphate

The skin produces cholesterol sulfate in large quantities when it is exposed to sunlight. Our theory suggests that the skin actually synthesizes sulfate from sulfide, capturing energy from sunlight in the form of the sulfate molecule, thus acting as a solar-powered battery. The sulfate is then shipped to all the cells of the body, carried on the back of the cholesterol molecule.

Evidence of the benefits of sun exposure to the heart is compelling, as evidenced by a study conducted to investigate the relationship between geography and cardiovascular disease (Grimes et al., 1996). Through population statistics, the study showed a consistent and striking inverse linear relationship between cardiovascular deaths and estimated sunlight exposure, taking into account percentage of sunny days as well as latitude and altitude effects. For instance, the cardiovascular-related death rate for men between the ages of 55 and 64 was 761 in Belfast, Ireland but only 175 in Toulouse, France.

Cholesterol sulfate is very versatile. It is water soluble so it can travel freely in the blood stream, and it enters cell membranes ten times as readily as cholesterol, so it can easily resupply cholesterol to cells. The skeletal and heart muscle cells make good use of the sulfate as well, converting it back to sulfide, and synthesizing ATP in the process, thus recovering the energy from sunlight. This decreases the burden on the mitochondria to produce energy. The oxygen released from the sulfate molecule is a safe source of oxygen for the citric oxide cycle in the mitochondria.

So, in my view, the best way to avoid heart disease is to assure an abundance of an alternative supply of cholesterol sulfate. First of all, this means eating foods that are rich in both cholesterol and sulfur. Eggs are an optimal food, as they are well supplied with both of these nutrients. But secondly, this means making sure you get plenty of sun exposure to the skin. This idea flies in the face of the advice from medical experts in the United States to avoid the sun for fear of skin cancer. I believe that the excessive use of sunscreen has contributed significantly, along with excess fructose consumption, to the current epidemic in heart disease. And the natural tan that develops upon sun exposure offers far better protection from skin cancer than the chemicals in sunscreens.

Cholesterol Sulphate and Heart Disease

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Red Meat: Another Red Herring?

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Sweet poison: why sugar is ruining our health

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...the risk of mortality or acute coronary syndrome was positively associated with age; male gender; hypertension; uncontrolled diabetes; being a former smoker; HAVING LOW LDL; having low BMI....

Vitamin D Levels for Preventing Acute Coronary
Syndrome and Mortality: Evidence of a Non-Linear
Association

doi: 10.1210/jc.2013-1185

J Clin Endocrinol Metab

Low LDL and low BMI associated with increased mortality risk