Link In Spacedoc’s newsletter this morning a link to a letter about eggs: In a recent Atherosclerosis article, Spence et al set out to determine if consumption of egg yolks leads to carotid vascular damage [1]. The authors’ suggested premise is that egg yolks are a rich source of cholesterol, making them a risk factor for cerebrovascular disease.How cholesterol became established as a risk factor for cerebrovascular disease despite a historically weak and inconsistent association appears in great detail elsewhere [2]. Suffice it to say,dietary cholesterol may have very little impact on serum cholesterol[3], and serum cholesterol may have very little impact on vascular damage [4] and cerebrovascular disease [5]. (Moreover, if serumcholesterol has any effect at all, it may be one of protection e.g.,against hemorrhagic and total stroke in hypertensives [5,6]). Lucan SC, Egg on their faces (probably not in their necks); The yolk of the tenuous cholesterol-to-plaque conclusion, Atherosclerosis (2012), http://dx.doi.org/10.1016/j.atherosclerosis.2012.10.076 In Defence of Eggs